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List of predicted targets

These targets have been predicted using the method described in:

Gfeller D., Michielin O. & Zoete V.
Shaping the interaction landscape of bioactive molecules, Bioinformatics (2013) 29:3073-3079.
Retrieve data:            
Query Molecule



General Target Classes
Target Common name Uniprot ID ChEMBL ID Probability* # sim. cmpds (3D / 2D) Target Class
Estrogen receptor ESR1 P03372 CHEMBL206
146 / 42 Transcription Factor
5-hydroxytryptamine receptor 6 HTR6 P50406 CHEMBL3371
4 / 2 Membrane receptor
Estrogen receptor beta (by homology) ESR2 Q92731 CHEMBL242
146 / 42 Transcription Factor
FAD-linked sulfhydryl oxidase ALR GFER P55789 CHEMBL1741189
11 / 4 Enzyme
Carbonic anhydrase 1 (by homology) CA1 P00915 CHEMBL261
17 / 22 Enzyme
Carbonic anhydrase 2 CA2 P00918 CHEMBL205
17 / 22 Enzyme
Carbonic anhydrase 3 (by homology) CA3 P07451 CHEMBL2885
17 / 22 Enzyme
Carbonic anhydrase 5A, mitochondrial (by homology) CA5A P35218 CHEMBL4789
17 / 22 Enzyme
Carbonic anhydrase 7 (by homology) CA7 P43166 CHEMBL2326
17 / 22 Enzyme
Carbonic anhydrase 5B, mitochondrial (by homology) CA5B Q9Y2D0 CHEMBL3969
17 / 22 Enzyme
Carbonic anhydrase 13 (by homology) CA13 Q8N1Q1 CHEMBL3912
17 / 22 Enzyme
Androgen receptor (by homology) AR P10275 CHEMBL1871
6 / 8 Transcription Factor
Arachidonate 5-lipoxygenase (by homology) ALOX5 P09917 CHEMBL215
22 / 25 Enzyme
Arachidonate 15-lipoxygenase ALOX15 P16050 CHEMBL2903
25 / 25 Enzyme
Arachidonate 12-lipoxygenase, 12S-type ALOX12 P18054 CHEMBL3687
25 / 25 Enzyme

* Probabilities have been computed based on a cross-validation. They may therefore not represent the actual probability of success for any new molecule (see FAQ).